Sentence examples similar to dependent essentials from inspiring English sources

The model was initially used to determine condition dependent essential metabolic genes (lethal genes) needed for growth and survival.

Lopez, G. & Anderson, J. C. Synthetic auxotrophs with ligand-dependent essential genes for a BL21 DE3) biosafety strain.

Lopez and Anderson12 developed an alternative biocontainment strategy that introduces ligand-dependent essential genes into an E. coli BL-21 strain.

Autophagy is a lysosome-dependent essential cellular catabolic pathway that serves to degrade cytoplasmic proteins, protein aggregates, and organelles (42).

These results suggest that the inviability of Hsp90 deletion mutants may result from the deficiency of Hsp90-dependent essential genes.

Erv1 has a long history in the literature and is a well-known FAD-dependent essential sulfhydryl oxidase in the yeast IMS.

Here we introduce a new paradigm for the design of combination therapy treatment strategies that exploits the tumor adaptive process to identify context-dependent essential genes as druggable targets.

Terrestrial plants are dependent on essential leaf physiological processes such as a continuous supply with water since photosynthesis cannot be dissociated from transpiration.

This cell polarity is N-cadherin/CIL dependent and essential for efficient chemotaxis.

Noteworthy, DNA and histone modifying enzymes are highly dependent on essential metabolites such as acetyl-CoA, iron, ketoglutarate, NAD+, and S-adenosyl methionine (SAM) and rely on a stable cellular metabolic state [ 12].

Antifolates such as methotrexate (MTX), pemetrexed and raltitrexed exert their cytotoxic activity via potent inhibition of folate-dependent enzymes essential for purine and pyrimidine nucleotide biosynthesis and thereby block DNA replication.