Although the reliability of PiCCO system has been found to be good in heterogeneous groups of patients, it is still questioned, mainly on the time-dependent accuracy on recalibrations and its variability on agreement at different vasopressor dose [30, 37, 38].
The reference-dependent accuracy is defined as the percentage of correctly aligned positions judged by the reference alignments.
As shown in Table 4, our pairwise potential can improve reference-dependent accuracy by 3% and reference-independent accuracy by 0.01, respectively.
In terms of reference-dependent accuracy, our method is better than HHalign by only 8.8 and 5.2%, which is not as big as reference-independent accuracy.
As our ultimate goal is to predict 3D structure for a target protein, reference-independent alignment accuracy is more important than reference-dependent accuracy.
Microarray measurements generally correlate with relative RNA molecule counts within optimal ranges but suffer from expression-dependent accuracy bias and precision that varies across datasets.
The reference-dependent accuracy is defined as the percentage of correctly aligned positions judged by the reference alignments, which are built using our in-house tool DeepAlign (Wang et al., 2013).
When the TM-score of two proteins under consideration falls into [0.65, 0.80], our method outperforms HHalign by ∼3.3% in terms of the reference-dependent accuracy and by ∼7.6% in terms of the reference-independent accuracy.
Inclusion of 50 ng/mL free LF contributed to higher LTx as expected since it was able to bind the excess free PA63 in the LTx sample.> Matrix-dependent accuracy was assessed because serum and plasma samples may have different components released during processing that influence LTx activity.
We also calculate the reference-dependent accuracy on Set6K and Set4K by allowing four-position off the exact match, as shown in Table 2, which indicates that our method is still much better than HHalign when four-position off the exact match is allowed.
Accurate rigid pavement design is heavily dependent on accuracy of these material inputs.
