For a pathway P with set of genes g 1, g 2, …, g k, the overall procedure is summarized as follows: 1) For each pair of g i and g j in P, the cooperation profile t ij, competition profile d ij, redundancy profile h ij, and dependency profile l ij are calculated for disease and control groups separately.
To identify such interactions, we use the minimum mRNA expression for pairs of genes to define the dependency profile of genes g i and g j as (4) l ij k = min e i k, e j k for 1 ≤ k ≤ m These four gene interaction profiles are conceptually illustrated in Figure 1.
Thus, we did not exclude hits based on the iron-dependency profile but noted the ratios as a possible indicator for the compounds' mechanism of action (for example, the isoquinoline diones series, Figure 2 and Table S1).
14 This tool measures the patient's needs and his/her care dependency (care profile), and assesses certain ailment risks (risk profile required for effective nursing).
"It is a profile of immigrants' dependency without any profile of their contributions".
In this article, we find an unusual and different way to incorporate pairwise dependencies into profile HMM.
In this paper, we investigate the impact of rules such as attribute aggregation and reference dependency on preference profiles for specific design attributes, as well as the design specification, as we vary the dimensionality of an SC design.
A co-transcriptional network was constructed from the microarray data using the ARACNE method, which uses mutual information (MI) to test statistical dependency between expression profiles [ 11].
In summary, the consistent transcript-dependent components of expression profile dependency on post chip RNA quality can be explained by the distribution of relative probe positions, the length of the mRNA, and probably the stability of the mRNA species.
