Exact(2)
Introduction of controlled changes into the expression dataset enables us to address many problems associated with pre-processing and analysis of microarray data, including the quality dependence of the analysis from the threshold of minimal gene expression, the influence of fold change restrictions, and other factors.
Given the dependence of the analysis on the duration of follow-up, in a second set of sensitivity analyses, we restricted the MRSA studies to include only those that reported clearance on or before the maximum observed follow-up time for the included VRE studies.
Similar(57)
To reveal the dependence of our analysis on the selection of LMF, we perform the same analyses of CM4 with different LMF.
A recent genome-wide association study of alcohol dependence in humans used genes identified by differential mRNA expression in alcohol-consuming rats as a means of attempting to generate more credence in the candidate genes with modest statistical support for association with alcohol dependence in the analysis of the human data [ 110].
The model presented here enables easy estimation of the dependence of analysis quality on the number of replicates.
These recursions have been derived in several different contexts, e.g. force induced RNA denaturations [ 6], the investigate of loop entropy dependence [ 9], the analysis of FRET signals in the presence of single-stranded binding proteins [ 5], as well as in mathematical studies of RNA panhandle-like structures [ 3, 4].
We analyzed the local sensitivity of the Fakhouri et al. model at parameter values optimized in their study using scheme 2. To reduce the dependence of local analysis on a single set of optimized values, we applied local sensitivity analysis in a global fashion.
Pooled estimates and 95% CIs were calculated using both a fixed-effects model (Mantel–Haenszel method) and a random-effects model (DerSimonian Laird method), allowing evaluation of the dependence of the conclusions of the analysis on the model assumptions.
This is because of the weak distance dependence of the interaction force in analysis.
An important role plays the load balancing in dependence of resource analysis and monitoring.
Therefore, more detailed controlled changes are necessary to better assess performance dependence of an analysis from expression level.
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