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Initially, animals were probably observed for practical reasons because early human survival depended on knowledge of animal behaviour.
The discovery of stellar associations depended on knowledge of the characteristics and motions of individual stars scattered over a substantial area.
Classic methods for the design of screening libraries have depended on knowledge of target structure and relevant pharmacophores for target focus, and on simple count-based measures to assess other properties.
Religion depended on knowledge and the correct practice of prayer, ritual, and sacrifice, not on faith or dogma, although Latin literature preserves learned speculation on the nature of the divine and its relation to human affairs.
The 'large-scale survey' experiment type is used for high-throughput screens involving large collections of mutant strains whose design and construction depended on knowledge of the genome sequence.
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Most genetic modifications have pleiotropic effects, so the meaningful interpretation of any one behavior often critically depends on knowledge of other phenotypes.
Adaptation depends on knowledge.
Does hierarchical event perception depend on knowledge of actors' intentions?
Successful innovation depends on knowledge – technological, strategic and market related.
Sustainable river basin management depends on knowledge, skills and education.
All professions, from medicine to law, will depend on knowledge of many cultures.
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