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Hox transcription factors bind nuclear DNA pervasively and regulate a plethora of target genes, deploying various molecular mechanisms that depend on the developmental and cellular context.
The results obtained also depend on the developmental stage or age of the cells.
It has been previously demonstrated that inhibitor compounds effectiveness may depend on the developmental stage of the parasite.
The outcome of infection with various pathogens, including C. albicans, in chick embryos has been described to depend on the developmental stage (age) at infection [17], [23].
The response to C. albicans infection shows some similarities to LPS challenges, but also displays different kinetics which partially depend on the developmental stage of the embryo.
A common feature of lateral inhibition by NOTCH signalling throughout the animal kingdom is that mediates the binary decision of adjacent cells between two alternative fates, which depend on the developmental context [9], [17].
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In summary, these results show that the degree of bilirubin-dependent cerebellar neurodegeneration in vivo depends on the developmental stage of the specific cell type.
Gene expression levels for enzymes involved in terminal steps to TAG biosynthesis in the ER further indicated that both acyl-CoA-dependent and -independent mechanisms might play a role in TAG assembly, depending on the developmental stage of the fruit.
Depending on the developmental stage, chemical exposure in the mother can result in different degrees of toxicity in the embryo or fetus.
Identical temperatures yielded qualitatively different results depending on the developmental stage.
Their action results in different outcomes depending on the developmental stage, tissue and/or cellular context.
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