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Unfortunately, the results strongly depend on the continuum solvation employed, making the absolute affinities unreliable or the method empirical (the solvation method can be selected to give accurate Δ G bind).
Ultimately, this implies the independence of V∞ on Qp and Qe and the fact that the contributions to the free energy from the matrix elements in eq 12.9 do not depend on the continuum or molecular representation of the solvent and related effective Hamiltonian used (see below) to compute the free energy.
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Dedekind perceived that the character of the continuum need not depend on the quantity of points on a line segment (or continuum) but rather on how the line submits to being divided.
These resolution dependent results affirm that reliable, predictive calculations for multiscale porous microstructures depend on the availability of large realistic continuum models.
The fragmentation process is modeled according to the crack initiation and propagation, which depend on the material damage levels and are estimated using continuum damage mechanics theory.
The expression of post-traumatic headache may depend on the underlying biotype of the patient - in our cases the biotype of hemicrania continua.
These investigations reveal a continuum of binding affinities in which multisite PTM recognition involves both switch- and rheostat-like properties, yielding graded effects that depend on the inherent 'reader' specificity.
The hybrid approach generally spends less computational time than the IP method for rarefied gas flows, and the numerical performance of the hybrid approach depends on the number ratio of continuum cells to particle cells.
Whether an individual moves from one end to another, along this continuum, depends on the encountered stressors and the set of coping resources available.
Importantly, the three stages are a continuum, the starting point for analysis found anywhere on this mitigation continuum depending on the pathogen in question and the specific disease situation.
The marketing efforts of a firm can be described by less or more entrepreneurial on a continuum depending on the environmental conditions the company is operating in (Morris et al. 2002).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com