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In this review we focus on RA, a highly heterogeneous autoimmune disease that is known to depend on multiple genes and environmental factors.
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Systems medicine is an emerging discipline that aims to address the problem that a disease is rarely caused by malfunction of one individual gene product, but instead depends on multiple gene products that interact in a complex network [ 7].
However, there is no single, universal process for the expression of all recombinant proteins in this host, because the levels of expression of a heterologous gene will depend on multiple variables that are specific to each recombinant system.
Obviously, all meat quality traits are complex traits that depend on multiple interacting factors, including genetic background, which may depend on species, major genes and gene interaction, and environmental background, which may depend on feeding, management and slaughter conditions [ 6].
Quality in hospital health services depend on multiple factors.
The reasons depend on multiple circumstances in the network.
It is likely that selection for regions of LOH depends on its effect on multiple genes.
All of these issues can be addressed using different strategies, however the success of these strategies depends on multiple features of the genes.
The extent of transgene expression largely depends on multiple aspects, such as gene delivery method, cellular physicochemical properties, and the traits of the construct [ 1].
A reasonable explanation is that not all genes of the genome are subject to DNA methylation-dependent regulation, and that gene regulation mainly depends on multiple regulation mechanisms.
The intracellular survival of S. aureus in neutrophils, as well as in non-professional phagocytes, depends on multiple virulence factors, including global regulators of gene expression [32], [40].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com