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Cachexia induced by the C26 tumor appears to depend on elevated interleukin (IL -6 plasma levels [18].
Furthermore, we investigated whether subclinical inflammation might influence susceptibility to traffic-related air pollution and tested whether the association between air pollution and diabetes might depend on elevated serum concentrations of complement factor C3c at baseline.
Taken together, our findings suggest that MTMR14 deficiency evokes severe inflammation via the up-regulation of TNF-α and IL-6, and the metabolic disorders may depend on elevated leptin and decreased adiponectin.
Cancers, including acute lymphocytic leukaemia, acute/chronic myeloid leukaemia, pancreatic cancer, breast cancer, etc, depend on elevated RAD51 functions and enhanced HR rate for their proliferation, survival and drug resistance capabilities (Raderschall et al, 2002; Skorski, 2002; Slupianek et al, 2001; Vispe et al, 1998).
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On the other hand, in T. divaricatum it was only nectar volume per flower that clearly depended on elevated temperatures.
Similarly, the extended lifespan of the nduf-7 (et19 ) mutant depends on elevated ROS because it is suppressed by the inclusion of an antioxidant in the culture plates.
In addition, the extent to which hypothalamic AGRP and POMC mRNA depends on elevated glucocorticoid levels in fasting and insulin deficiency has not been determined to date.
Growth of the transplantable EMR-86 rat mammary carcinoma depends on elevated prolactin levels which are induced by oestrogenic stimulation of the pituitary.
Reporter assays monitoring the activities of histone acetyltransferases or histone deacetylases, respectively, suggest that hypoacetylation most probably depends on elevated sirtuin deacetylase activity, but not on class I/II histone deacetylases.
To test whether the enhanced differentiation observed in Ras cells depends on the elevated checkpoint activity in response to cytarabine, we incubated control and Ras cells for 24 hours with cytarabine in the presence or absence of caffeine, an inhibitor of the Atm and Atr kinases [34].
Additionally, it highly depends on the elevated expression of VEGFR-2.
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