Sentence examples for density of carriage from inspiring English sources
Approximately 50% and 40% of pneumococcal carriers had a density of carriage of >1 in the postvaccination surveys.
A high density of carriage among young subjects might partly explain why children are more efficient than adults in pneumococcal transmission.
Most pneumococcal carriers (83%) had a density of carriage of >1, and this was similar among VT (87%) and NVT (82%) carriers.
If reduction in the density of carriage results in less effective transmission, as seem likely, this could be an important mechanism through which PCVs exert an indirect protective herd effect.
Reduction in density is also in agreement with the hypothesis stated above, which asserted that accelerated clearance (that would lead to a shift to a lower density of carriage) rather than inhibition of colonization may be an important mechanism of protection against pneumococcal carriage acquired either through natural exposure or through vaccination [ 24].
In the vaccinated villages, there was a significant decrease in the density of carriage with any pneumococcus following vaccination in individuals older than 5 years (from 2.44 to 1.88; difference = −0.56; P = .001) and a decrease of borderline significance among the younger age group (from 2.57 to 2.11; difference = −0.46; P = .07) (Table 3 A).
The data from our study indicate that culture and qPCR are highly complementary for studying pneumococcal carriage episodes, especially when the carriage density is low.
Prevalence and density of gametocyte carriage were evaluated in asymptomatic and symptomatic infections by examination of Giemsa-stained blood smears and/or RT-PCR (for falciparum in one site).
Our main finding was that the density of pneumococcal carriage decreased with increasing age.
Time-trends analysis revealed that pneumococcal vaccination appeared to lower the density of nasopharyngeal carriage.
We also showed in a before-after analysis that the density of pneumococcal carriage was lower after vaccination.
