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In consideration of the resolution of signal detection, signals within 1 Kb apart were merged for both optical molecules and optical contigs to improve alignment accuracy at regions of dense signals.
Aggregates of nanoparticles appear as dark, optically dense signals under bright field, that correlate with a refringent signal under dark field and phase contrast [ 11].
In E. humeralis, in situ hybridization with the specific probes Cy5-EhSym16S and TNKM16S-A555 denseted densignalsals in the content of the midgut crypts.
Unexpected GWAS findings were another focus: the first generation of GWASs did not show the expected 'Manhattan skyline' of dense signals, and loci reported by GWASs so far explain only a small proportion of the observed phenotypic variation.
Except area 46, both ROBO1 and ROBO2 mRNAs showed dense signals in layer II (Fig. 4 B, f, i, l, arrowheads), and the signal intensity gradually decreased toward the deeper layers.
In brief, by simulating 10,000 random points followed by 3D distance measurements toward (1) the nearest chromocenter surface (defined as DAPI dense signals) and (2) the nuclear periphery (defined as edge of the DAPI signal), we generated a background distribution for each analyzed nucleus.
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It is worth noting that the Nexus 5 holds a 4G signal better than quite a lot of other smartphones currently available, suggesting its signal reception is solid most of the time, even in the dense signal black spots of London.
In the 1980s, the theory of Euclidean lattices became of great interest for the design of dense signal constellations well suited for transmission over the additive white gaussian noise (AWGN) channel.
To this end, muscle lysates were probed with an anti-Ub antibody and, as shown in Figure 4B, Ub-positive proteins were distributed over a large range of molecular weights with the most Ub dense signal appearing above 250 kDa.
A dense signal was observed for the interaction of F-WT-NACC1 and H-PML, but signals for K167R or SIM/M were markedly reduced (Fig. 6b).
Similar to SUMO-1, SUMO-2/3 localizes in two predominant subnuclear patterns: a single, dense signal near the centromere of human chromosome 9 and small, individual foci co-localized with autosomal centromeres.
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