Twenty-four hours after treatment tumor cells in the viable tumor rim appeared disorganized and less dense than in the control or at 1 h time point (Fig. 1, 24 h treated); however, also fewer cells were caspase positive (Fig. S1, 24 h treated).
Stroma appears less dense in the Imatinib-treated vs the control group.
In addition, the matrices of many of the small mitochondria in p32 siRNA-treated cells appeared less electron-dense than those in the control cells.
Moreover, in presence of cyclopamine the colonies were less dense than the control colonies, which is consistent with the effect of cyclopamine on cell proliferation.
Masson's trichrome staining showed thick, dense, and disorganized collagen fibers in the control wounds), whereas the collagen fibers were thinner and arranged more regularly and parallel in the experimental wounds).
Masson's trichrome staining showed thick, dense, and disorganized collagen fibers in the control wounds); thin more regularly arranged fibers with increased number of small blood vessels in the 100 nM nAG experimental group); and faint staining with sparse thin collagen bundles and increased vascularity in the 150 nM nAG experimental group).
But the occipital lobe at the rear of the brain, where vision and visual perception occur, is also denser and simpler than in the control, with far fewer folds and indentations.
Moreover, in both PTH-treated groups the regenerate callus was visually denser and larger than in the control group.
As in the control muscles, dense rows of mitochondria were sandwiched between the bundles of contractile elements perpendicular to the Z bands.
At 6 weeks, the trabecular bone in the control group appeared thick and dense, while the trabecular bone in the experimental group had become lamellar bone.
