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In the spaceship, the crew cabin would be on top, with flat packed, dense cargo compartment underneath.
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Theoretical (Derganc et al., 2013) and experimental studies (Stachowiak et al., 2012) indicate that highly dense cargoes could mediate budding by asymmetric crowding.
Recently more insight was gained into the role of another dense granule cargo molecule, polyphosphate (polyP).
Specialized secretory organelles known as micronemes, rhoptries and dense granules deliver cargo proteins in a coordinated fashion during the invasion process [4].
This may be another plausible explanation for the ability of APL-1 to regulate synaptic transmission as dense core vesicle cargos have been found capable of modulating cholinergic signaling [49].
This bidirectional helical motility may allow dynein to avoid roadblocks in dense cytoplasmic environments during cargo transport.
During this maturation process, insulin is crystallized in the form of dense core, and unwanted cargoes and membrane proteins are removed and transported either back to the TGN or endo/lysosome systems (Kim et al. 2006).
Bidirectional helical movement may provide additional flexibility to dynein to transport cargos in dense cellular environments.
For instance, in axonal transport some cargoes, such as dense core vesicles and synaptic vesicles, are inefficiently captured at synaptic boutons and circulate within the axon (Wong et al., 2012), whereas others, such as mitochondria, are stably retained at synapses (Kang et al., 2008).
Moreover, fiber structure is maintained even upon dense conjugation with a model bioactive cargo OVA257-264 peptide.
Bulk cargo can be very dense, corrosive, or abrasive.
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CEO of Professional Science Editing for Scientists @ prosciediting.com