Exact(1)
All countries had a public health surveillance system that included a large number of infectious diseases, but some countries had at national level a special dengue unit (Brazil, Dominican Republic, Indonesia, Sri Lanka and Vietnam).
Similar(58)
Special dengue units were perceived to be very helpful for clinical management (particularly in Peru, Malaysia, Sri Lanka and Vietnam).
In Asia 12 of the 20 hospitals had epidemic response plans and particularly Malaysia, Sri Lanka, Vietnam had special dengue units for enhanced dengue clinical management.
An additional two patients with anti-dengue IgM antibodies detected by AFRIMS MAC ELISA were positive for anti-JEV IgM antibodies by the Panbio RC ([patient 1] 6.7 JEV Panbio units together with 3.3 Dengue Panbio units, and [patient 2] 7.4 JEV Panbio units together with 8.5 Dengue Panbio units).
This could be argued as under-hospitalization and this practice cannot be generalizable to healthcare settings lacking dedicated dengue care units that can closely monitor the cases.
Patients with anti-dengue IgM units < 40 U and anti-JEV IgM units > 40 U were classified as having acute JEV infection.
One patient with anti-dengue IgM antibodies by the AFRIMS MAC ELISA was also positive for anti-JEV IgM antibodies in the Panbio ELISA (16.0 Panbio units for JEV IgM and 3.7 Panbio units for dengue IgM) using both the PanBio SI and modified Panbio RC.
ALT: (Alanine aminotransferase); AST: (Aspartate aminotransferase); GGT: (Gamma glutamine transferase); Alk.Phos: (alkaline phosphate); IU: (International units); DHF: (Dengue hemorrhagic fever); DF: (Dengue fever).
Finally, we relied on the provincial divisions of Peru, which are not necessarily the most meaningful spatial units for dengue disease dynamics [ 16, 46].
In this trial, we used a 2× cut off for increase in dengue virus specific IgG units in saliva samples collected before and after the dengue season, based on a previous study.
Comparison of Panbio unit results for dengue-positive and dengue-negative samples as determined by using the assay interpretation criteria (Table 2 and Figure 2).
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