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To date most applications have been demonstrations of proof-of-principle; widespread use by people who could benefit from this technology requires further development.
The proof-of-principle trial objectives are: safety; dose selection and schedule of vaccination; and demonstration of proof-of-principle.
Most recently, the success with bevacizumab in advanced metastatic colorectal cancer was an encouraging demonstration of proof-of-principle of an anti-VEGF approach.
Demonstration of proof-of-concept in a Phase IIa CHMI study that an effective BSV can significantly impact PMR in vaccinated volunteers.
The difference maker to me here is that any sort of indoor or micro-location system now has to battle upstream from demonstration to proof-of-concept to acceptance to licensing and/or acquisition.
The rich literature related to social choice and voting theory provides various alternative demonstrations of the proof (e.g. [ 38]).
Demonstrations of space-proof cavity designs for MAQRO in relevant environments are planned in the near future.
He pointed to the two big demonstrations as proof of the city's commitment to equality and safety, and added that none of the suspects arrested were from Pamplona.
Slaoui said: "It was the first demonstration of the proof of concept that we were able to make a vaccine that killed the parasite in the blood and also in the liver".
However, demonstration of clinical proof of principal should increase interest and competition from large pharmacological companies.
"The greatness of yesterday's demonstrations were proof of the energy of our democracy".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com