Sentence examples for demonstration that the functional from inspiring English sources

The merit of this explanation is the qualitative demonstration that the functional form of a PMF can be obtained from probabilistic reasoning.

Perhaps the most clear-cut result with a profound impact on interpretation of HD pathogenesis is the demonstration that a functional polymorphism in the brain-derived neurotrophic factor (BNDF) gene does not modify age at neurologic onset [ 13- 16].

As shown in fig. 4e, whereas in wild type cells H3-K27me3 decreased by about 60-70% at day 7 of differentiation, in Jmjd3-kd clones it remained at the same level observed in undifferentiated cells (normalization for total H3 levels is shown in Supplementary fig. S8), thus providing a functional demonstration that Jmjd3 demethylates H3-K27me3 athehe Nestin TSS.

A striking recent example of the latter type of achievement is the demonstration that different functional categories of genes scale differently with genome size, with the steepest ascent of regulatory genes offering a plausible explanation for the observed limits of genome size in prokaryotes [ 32].

One interesting observation of these experiments is the demonstration that a functional AS can promote cell shape changes and coordinated behavior in the otherwise mutant epidermis.

On the basis of the demonstration that functional and neurochemical changes in the MOC take place with age, we would expect a decrease in MOC function in older people.

The demonstration of the functional nature of sr1, sr2, srX, and sr3 suggests that these regions contribute to the activity of the protein.

This began with the cloning of the melanocortin 1 receptor (MC1R) gene from human melanocytes and the demonstration that the encoded receptor is functional.

The demonstration that functional NHEJ contributes to the cytotoxicity of such inhibitors suggests that HR-deficient cancers with diminished NHEJ will be relatively resistant.

To have a final functional demonstration that isolated cells behave like EPCs in vivo, we injected them into rat muscles subjected to ischaemia/reperfusion injury.

A demonstration of the functional importance of the p63-FGFR connection was provided by experiments showing that the hypo-proliferative phenotype of keratinocytes with the p63 mutation could be rescued by increased FGFR expression and signalling.