Sentence examples for demonstration of t from inspiring English sources

However, other than Li et al.'s report, there had been no demonstration of T cell responses against this protein.

CML diagnosis was based on the demonstration of a BCR-ABL fusion transcript expressed by the Philadelphia (Ph) chromosome by RQ-PCR and/or the demonstration of t(9 22)(q34;q11) by conventional karyotyping or interphase FISH.

Accordingly, whereas the demonstration of t(12 21) and t(4 11) at birth implies the presence of leukaemic or leukaemia-predisposed cells, strictly speaking, no direct inference as to genetic events critical to leukaemia development can be made from the presence of leukaemia-specific TcR and IgH gene rearrangements (Taub et al, 2002).

Demonstration of T-cell cross recognition of epitope sequences from different clades may offer hope for a global vaccine.

Our demonstration of T-cell molecular mimicry may stimulate further evaluation of the potential role of the Clostridium species in NMO pathogenesis.

Thus, our manuscript is the first causal in vivo demonstration of how T cell/dendritic cell interactions can be modulated to determine T cell phenotype in a way directly relevant to human and animal health (as stated by Reviewer 2).

In determining this, CA IX knockout has been a unique tool allowing us to provide the first demonstration of a T tubular pathway for lactic acid.

The results presented here represent the first demonstration of CD8+ T cell-dependent control of tumours growing outside the treatment field following PDT; other studies showing inhibition of tumour growth outside the PDT treatment field have not discerned the effector cell type required for control of distant tumours (Gomer et al, 1987; Blank et al, 2001; Castano et al, 2003).

An essential element of the Conceptual Design Review (CDR) of these TBSs is the demonstration of capability of Test Blanket Modules (TBM) and their shields to fulfil their function and comply with the design requirements.

The central nervous system has long been considered an immune-privileged site, but this view has become more nuanced and complex with the demonstration of activated circulating T cells that cross the blood-brain barrier, rejection of tissue grafts placed in cerebral ventricles, and drainage of cerebrospinal fluid into extracranial lymph nodes18.

Interestingly, despite the clear demonstration of TLR5 on circulating T cells, purified T lymphocyte populations were not responsive to the TLR5 ligand flagellin nor were they responsive to soluble products of PBMC preparations in which flagellin responses were demonstrable.