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Importantly, the in vivo model allows definition of the behavioral consequence of the spinal drug action and permits demonstration of an effective therapeutic rationale which likely reflects the access of the intrathecal drug to deeper neurons.
Demonstration of HER-2 antigen overexpression in breast cancer constitutes the rationale for treatment with Trastuzumab (Baselga et al, 1998).
Providing a demonstration of key modeling capabilities needed for this type of study was the rationale behind this report.
The detrimental role of oxidative damage in critical pathologies, added to the demonstration of potential positive effects of albumin infusion in these patients, constitute a strong rationale that justifies for addressing the specific antioxidant capacities of HSA [11 14].
The detrimental role of oxidative damage in critical pathologies, added to the demonstration of potential positive effects of albumin infusion in these patients, constitute a strong rationale that justifies for addressing the specific antioxidant capacities of HSA [ 11- 14].
The demonstration of the binding specificity of mAb 62-71-3 to the RV glycoprotein at a molecular level provides an important rationale for including mAb 62-71-3 in RV-neutralizing antibody cocktails.
This is the first demonstration of the use of biodegradable nanoparticles to deliver genome-editing agents to human primary cells, and provides a strong rationale for systemic delivery of complex nucleic acid mixtures designed for gene correction.
Thus, even though the primary mandate had previously been safety of drugs, the rationale that led in 1962 to section 355 d) evolved from recognition of the importance of effectiveness for the demonstration of safety.
Demonstration of the lamp.
A demonstration of turn-by-turn directions.
Writer saw a demonstration of the fibrescope.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com