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The most direct causal evidence for microbial triggers for ReA derives from a demonstration of microbial antigens in the joint [ 16].
Until such studies are performed that rigorously utilize such a cause-and-effect approach, the demonstration of microbial endocrinology as a viable mechanism governing gut-microbiota-brain communication will remain largely hypothetical.
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The demonstration of such a microbial organ-specific nervous system would understandably have profound implications both on basic scientific as well as clinical thought since this would suggest that such a functioning "cognitive" system within the gastrointestinal tract must interface with the host to enable and perpetuate its own existence.
We have provided a proof-of-principle demonstration that microbial community ecology of decomposing corpses has potential to be developed into a complementary forensics tool for estimation of PMI.
Diagnosis of this obligate intracellular bacterium is based on the demonstration of the microbe or microbial DNA in tissue specimens or faecal samples, or the demonstration of L. intracellularis-specific antibodies in sera.
Cultivation of this obligate intracellular bacterium is difficult and the diagnosis is therefore based on demonstration of the microbe or microbial DNA in tissue specimens or faecal samples by techniques such as PCR [ 4].
The recent demonstration of cathodic nitrate reduction in a microbial fuel cell (MFC) creates opportunities for a new technology for nitrogen removal from wastewater.
Demonstrations of microbe-mediated mineral formation in biofilms implicate this mode of microbial life in geological evolution and remediation of inorganic contaminants.
However, that work relied on an indirect coupling approach that was effective for initial demonstration but may not be extensible to more complex problems that are of significant interest (e.g., communities of microbial species and multiple constraining variables).
The Concept and Causes of Microbial Species.
Moreover, this loss of microbial diversity appears to be cumulative.
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