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As a demonstration of functionality, ion-exchange of the dopant tosylate for the anionic drug dexamethasone phosphate (dexPˉ) was explored.
Research prospects for new biomarkers of TBI should focus on demonstration of functionality in converging pathways that can impact multiple pathophysiological cascades.
The resurrection of ancestral proteins and viruses [ 4, 5] coupled with demonstration of functionality is now increasingly common and such studies are providing important insights to molecular evolution [ 6- 8].
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However, demonstrations of functionality in living systems necessitates a method to assess the in vivo stability of the relevant nanostructures.
For demonstration of machine functionality in this paper, the measured results of some fatigue tests have been presented in order to show the efficiency of the system.
A demonstration of the functionality of BEARKIMPE-2, with three nitroaromatic compounds showed that the differences in reaction rates for these compounds could be attributed to differences in their sorption behavior rather than their propensities to accept electrons in the reduction process.
Although lux has been previously used in whole animal BLI [16], this is the first demonstration of its functionality outside of a bacterial host.
For a further demonstration of the functionality of VHHs produced in larva, we performed in vivo protection experiments against RV A in newborn mice.
This approach is more efficient than other two-step molecular methods based on detection of specific gene sequences and subsequent demonstration of their functionality, but it can be hampered by potential incompatibility between donor and host expression machineries [ 20– 20].
Finally, although a conclusive demonstration of the functionality of ectopic GC-like structures in SS is required, Ig V gene rearrangement analysis has provided evidence of an antigen-driven B-cell response within microdissected GC-like structures in salivary glands of SS patients, suggesting their functionality in generating a local (auto) antibody response [ 38].
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