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This is the first demonstration of effective delivery of antibody mimics into cells, which could allow researchers to develop new drugs for cancer and many other diseases, says Pentelute, the senior author of the paper.
The demonstration of MPO delivery to neutrophil phagosomes at the electron microscope level is shown (Fig. 4).
These findings provide proof of the concept demonstration that delivery of 3-BP to the mitochondria using the NP system results in enhanced uptake and cytotoxicity in cancer cells.
It is uncertain as to whether students learn as effectively from video as from live demonstrations , although delivery of demonstrations of clinical skills through creation of enduring online video resources is cost-effective.
There are far too many South Park underpants gnome business plans around (Step 1: Offer behavior app, invoking BJ Fogg; Step 2; Step 3: Profit), and comparatively few robust demonstrations of value delivery here.
To our knowledge, we report the first successful demonstration of the active delivery , using macrophages, of nanoparticles to brain metastases and it paves the way for testing this method to deliver other nanovectors including nanorods, hollow nanospheres in the sub-100 and sub-50 nm range as well as nanoformulated therapeutics.
A number of demonstration projects evaluating delivery of PrEP are underway in the US [ 14– 20], and several more are taking place and/or being planned in sub-Saharan Africa [ 21– 23].
This observation is consistent with the demonstration of TALEN activity by delivery of TALEN-loaded LPs. 6) The authors should show how plasmid transfection compares to LP delivery of ZFNs/TALENs to understand whether LP-delivery is generally more efficient than plasmid delivery for multiple reagents, like is shown in Figure 5C, or if the CCR5 ZFNs are somehow special in this regard.
The biotechnological approach to create exosome-based delivery systems used by Alvarez-Erviti et al. was the first demonstration of an exosome-based drug delivery system which showed efficient in vivo delivery of siRNA [ 29].
Thanks to some handiwork by his uncle, Dean Fisher, young Evan now has documentary evidence of Santa's existence, as well as a demonstration of his magical present-delivery technique.
This demonstration of aptamer-mediated, cell-internalizing delivery of large RNAs with retention of functional structure raises the possibility of manipulating endosomes and cells by delivering large aptamers and regulatory RNAs.
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The phrase "demonstration of delivery " functions as a noun phrase, typically serving as the subject or object of a sentence. It refers to the act of showing or proving that a delivery has occurred, and the method of confirming the arrival of something at its intended destination.
Expression frequency: Missing
