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The recent PROMID study suggests that even asymptomatic patients may benefit from these agents with demonstration of delayed progression compared with patients treated with placebo.
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It might consist in the demonstration of a delayed risk 9 or in the censoring of information on exposures started during the suspected prodromal phase.
The concurrent demonstration of benefit in terms of delayed SREs and improvement in all biochemical end points (ie, PSA, total ALP), which would be expected with a therapy of Ra's mechanism of action, adds to the robustness of this finding.
1, 27, 28 Thus the demonstration that CSD clusters occur and can reduce brain ptiO2may go some way toward explaining the variable association of delayed ischemia with proximal arterial vasospasm, 29 and the existence of such a dual mechanism of delayed ischemia.
The public demonstration was delayed and then cancelled because of technical difficulties.
After being served his eviction notice by the city authorities at the start of the year, Lindenau was due to move out of his shop by 9 August, but a series of demonstrations helped delay an enforcement of the ruling until after local elections in September.
The demonstrations are delayed 24 hours for trivial reasons.
Even though delay-induced instability is widely discussed in theoretical literature for negative feedback systems [41], [43], [44], a direct demonstration of the interaction of delay and negative auto-regulation using gene circuits has not been shown both experimentally and theoretically.
Initial clinical evaluation of new therapies in cancers that are prevalent in the Western population is the standard in pharmaceutical development and delays demonstration of their possible use in the Asian population.
Bangkok endured its second consecutive day of mass street demonstrations aimed at delaying a Feb. 2 election that the ruling government is expected to win.
Among the three mechanisms converting triplet to singlet excitons, triplet fusion delayed fluorescence (TFDF) plays a key role in the demonstration of highly efficient and reliable OLEDs, especially blue devices, for practice applications.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com