Sentence examples for demonstration of binding from inspiring English sources

Whilst such approaches do not necessarily require the demonstration of binding legal or corporeal effects, they nonetheless often have forms of conditionality that will limit their application.

Specificity of the vitronectin antibody was confirmed by ELISA demonstration of binding to purified recombinant vitronectin, but not fibronectin or collagen (not shown).

The PfRH5 protein immunogen was pure and shown to be correctly folded by demonstration of binding to its receptor, basigin (Crosnier et al., 2011).

Nevertheless, two independent in-solution fluorescence-based assays along with demonstration of binding to an immobilized peptide are consistent with the computational prediction of the CaM-binding site as helix E of BRI1 kinase subdomain VIa.

Our demonstration of binding of tau to Syk is consistent with tau being a specific substrate for Syk and for their involvement in a cell-signaling pathway in neurons.

In both a radiometric competition assay and the fluorescence binding assay the synthetic JH III agonist methoprene specifically competed with JH III for binding to dUSP, the first demonstration of specific binding of a biologically active JH III analog to an insect nuclear receptor.

Multiple direct targets have been confirmed through demonstration of EWS/FLI1 binding to their promoters including insulin-like growth factor (IGF) binding protein 3 and the Aurora A and B kinases [ 67].

To our knowledge, this is the first demonstration of picomolar binding by a psychoactive compound that is not to a cell surface receptor.

This hypothesis was confirmed by the demonstration of direct binding of Ndk to Rab5-GTP and its dephosphorylation, consistent with the observation of reduced recruitment of the Rab5 interacting effector EEA1 to phagosomes containing Ndk-coated latex beads.

The transactome completes the tripartite components, which include demonstration of physical binding of a transcription factor to its target genes by chromatin immunoprecipitation (ChIP-chip or ChIP-PET) and mRNA level changes (as determined by standard gene expression profiling with microarrays).

The validity of this modeling was confirmed independently by the demonstration of direct binding of human TACC2 to the nuclear hormone receptor RXRβ.