This is therefore the first demonstration that chemokines, in combination with a cytokine, are required for leukocyte mobilization during a specific inflammatory reaction.
The importance of estrogen actions in the etiology of prostate cancer (PC) has been widely accepted following the demonstration that androgens, in combination with estrogens, can induce neoplastic lesions in the prostate [ 1].
In veterinary medicine, diagnosis is similar, but as there is no accepted 'gold standard', diagnosis is based upon the presence of haemolytic anaemia in combination with the demonstration of spherocytosis, positive in-saline auto-agglutination and/or Coombs' test [ 2].
Another Phase I study 65 evaluated the safety and preliminary clinical activity of the HCQ and temsirolimus (an mTOR inhibitor) combination in patients with advance solid tumors, following preclinical demonstration that HCQ enhanced cell death in combination with temsirolimus (CCI-779).
Shenhua Ordos CCS project is the first Chinese pilot-scale demonstration for CO2 deep saline aquifer storage in combination with direct coal liquefaction (DCL) production.
The second aim of Experiment 1 was to provide a demonstration of how Mantra can be used in combination with E-Prime (Schneider et al., 2002).
Mirkarimi et al. [ 6] found that both videotaped and live demonstrations were equally effective and can be used in combination or as an alternative for each other in teaching how to apply fissure sealant.
The demonstration of impaired hearing threshold in the high frequency range in combination with the perception of a high-pitched tinnitus might reflect a very useful element in the counseling of tinnitus patients.
We believe that the UNICEF BCO should move towards leveraging in a gradual but sustained, deliberate, and clearly articulated way in combination with a solid field presence oriented towards demonstration.
Our RNA-seq data in combination with ISH and electrophysiological recordings provided a clear demonstration that Cav3.3 is a specific marker of C-LTMRs and offers a new possible selective pharmacological target to control C-LTMRs' excitability in mice.
Over 30 patients have been treated worldwide using the current protocols, and recent trials provided the demonstration of long-term clinical efficacy of HSC gene therapy for SCID-ADA in combination with gene and cell therapy.
