Although the faint high molecular species of insoluble alpha-synuclein may be insufficient for microscopical demonstration, these data are compatible with a mild or early stage of pathogenesis.
Most importantly, the experiments here provide a demonstration, though the data are still preliminary, that the estimation techniques developed by Deng and Lynch (1, 2) are promising in characterizing deleterious genomic mutations in natural populations.
For a better graphical demonstration, all data were normalized by setting the means of non-exposed controls to the value 1. Afterwards, all single data were calculated as a ratio to control.
The demonstration confirms that geochemical data are valuable additional information for reservoir characterization, and shows that integration of geochemical data into reservoir simulation procedures can improve reservoir simulation models.
These data are the first demonstration that the antibacterial activity of ketoclomazone against E. coli and H. influenzae is due to the inhibition of DXP synthase activity by ketoclomazone.
Theses data are the first demonstration of a compensatory upregulation of PDE4B gene expression in response to DP action in Teff cells.
As such, our data are the first demonstration of enzymatic intervention of a member of the PPI superfamily in protein quality control in the ER of living cells.
The data are a clear demonstration of ethylene involvement in Cd- and CPT-triggered cell death.
As RFP2 is known to remove orphan subunits of multimeric complexes (34, 35), our data are the first demonstration that RFP2 also handles misfolded mutated proteins.
These data are the first demonstration that dose addition correctly predicts the neurotoxic effects of a pyrethroid mixture composed of low-level, equitoxic doses of the individual chemicals.
