Exact(3)
Both set of leaders face credible evidence demonstrating their roles in atrocities, so there will be tremendous pressure to strike a deal, which will only get stronger as the deadline approaches.
Importantly, the identification of several of these was also supported by experimental evidence in the literature demonstrating their roles in regulating expression of at least some of the target genes (Additional File 1: Supplemental Table S4).
In the present study, proteins S100A12, S100A8 and S100A9, were up-regulated by 11.17, 5.1 and 5.1 folds in the mastitis-infected mammary glands, which is consistent with the previous report, further demonstrating their roles in the immune response to pathogen infection.
Similar(57)
To investigate the in vivo functional roles of EHD proteins we have previously employed a gene knockout approach and such studies of Ehd1 and Ehd4 have demonstrated their roles in normal murine development and physiology [27] [28].
Further qPCR analysis of these proteins at the mRNA level demonstrated their roles in glycolysis.
Initial studies on ILC2s demonstrated their roles in innate immunity against a variety of infectious organisms.
Work is currently underway to characterize each of the targets and to demonstrate their roles in virulence.
Finally, to demonstrate their roles in the etiology and pathogenesis of obesity, we tested whether the genes harboring the DVCs or DMCs showed significantly enrichment of genes identified by genome-wide association studies on obesity and its related diseases.
Using a microarray approach, Kang and colleagues identified several genes involved in the generation of breast cancer metastasis in bone and demonstrated their roles in bone colonization in vivo.
The high content of polyunsaturated fatty acids likely demonstrates their role as cryo-protectants, helping algal cells to maintain membrane fluidity and preventing intracellular ice crystal formation30.
The conventionalization of germ-free mice demonstrated their role in enteric neuron biology and the gut-brain-periphery axis.
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