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Further, PIM2 triggered phosphorylation of AKT and 4EBP1 (Figure 2C) clearly demonstrating the activation of PI3K pathway.
The induction of apoptosis was confirmed by annexin V-positive/propidium staining and by demonstrating the activation of caspase-3.
To our knowledge, this is the first study demonstrating the activation of fermentative metabolism after OPP treatment in S. aureus.
In patch clamp assays, we observed that heterologously expressed AtCNGC10 conducted significant inward K+ currents with the application of dibutyryl cGMP (100 uM) in the extracellular recording solution, demonstrating the activation of these channels [ 5].
Zhang et al. (2011) identified gene expression profiles of short-term cultured PBMCs from ALS patients, demonstrating the activation of monocytes/macrophages via the LPS/TLR4 neuroinflammatory pathway [ 13].
Prospective events demonstrating the activation of JAK2/STAT3 pathway and the involvement of residual CSC-like cells in response to chemotherapy treatment, which are the ultimate source of recurrent disease, are depicted in Figure 13.
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These data demonstrate the activation of AHSV specific T-cell epitopes during vaccination with rMVAs expressing VP2 and NS1.
Taken together, these results demonstrate the activation of caspases and cleavage of tau in the AD brain, events which may precede and lead to the formation of NFTs.
In transfected cell lines it has been demonstrated the activation of D2DR induces a significant negative regulation of A2AAR-mediated responses, whereas few data are at now available about the regulation of A2AAR by D2DR agonists at receptor recognition site.
Earlier studies also demonstrated the activation of MAPKs in the plants exposed to salinity (Munnik et al. 1999).
We demonstrated the activation of caspase 3 in Myc down-regulated cells also using the siRNA methodology.
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