Sentence examples for demonstrating that activation of from inspiring English sources
However, addition of heregulin1-β 1 abolished the inhibitory activity of ICI 182,780 on MCF-7 cells, demonstrating that activation of the HER-2/neu receptor signalling pathway can override the growth inhibitory effect of ICI 182,780.
Inactivation of ErbB2 was also associated with a decrease in the level of ErbB3 PI-3K complex and the activity of the PI-3K target, protein kinase B (PKB), demonstrating that activation of the PI-3K pathway was downstream of this receptor.
Our results are in line with those recently reported by Ogawa et al. demonstrating that activation of the AKT pathway is necessary for ΔNp63α protection against UV induced apoptosis [58].
A striking and prominent example of this was a recent report demonstrating that activation of GABAA receptors alters embryonic stem cell proliferation in cell culture as well as cell proliferation in mouse blastocyst stage embryos [48].
The ability of E2F1 to induce the activation of S6K was also studied in Saos-2 and PC12 cells, demonstrating that activation of mTORC1 by E2F1 is not a cell type phenomenon (Fig. 3D).
Importantly, rIFN-γ mediated inhibition in BMDM was not observed in IFN-γR−/− macrophages, demonstrating that activation of the IFN-γ signaling pathway is responsible for the observed inhibition of bacterial replication.
Here we demonstrate that activation of platelets with thrombin receptor activating peptide (TRAP) significantly increased IL-27 levels in supernatants.
We demonstrate that activation of GITR signalling inhibits NF-κB-dependent transcriptional activity while facilitating Erk activation in these neurons.
However, we also demonstrate that activation of the p38/MK2/Hsp25 pathway by BMP-2 is independent of the activities of either Cdc42 or PAK1.
Fan et al. demonstrated that activation of the EGF receptor in mammary cells caused the activation of Yap [109].
These data demonstrate that activation of EW after EtOH is unrelated to hypothermia or stress.
