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Using a genetic assay for loss of heterozygosity, we found that this centrin mutant showed increased genomic instability compared to wild-type cells, and we determined that the increase in genomic instability was due to a 100-fold increase in chromosome loss rates compared to wild type.
RESULTS: The HILP patients had a lower rate of locoregional recurrence (P=.028) and demonstrated increased survival (P=.026) compared to the control group.
Trophoblast cells treated with both AM and 1% CSE demonstrated increased cellular invasion compared to NS controls (1.5-fold [P <.01] and 1.45-fold [P <.01], respectively).
ATRX-negative and DAXX-negative tumours demonstrated increased CNV as compared to positive tumours (Fig. 1F).
The mesenchymal cells demonstrate increased sensitivity to genotoxic agents compared to epithelial cells.
Both obese and normal-weight individuals demonstrated increased gaze duration for food compared to non-food images in the fasted condition.
However, an early study comparing tumour genetics in NSCLC between patients with and without HIV demonstrated increased microsatellite instability in tumours from HIV-infected patients (Wistuba et al, 1998).
To follow up on the study demonstrating increased embryonic lethality and genomic instability caused by BPA [ 15], we have assessed the low-dose effects on adult behavior as a function of embryonic exposure.
Previous studies have demonstrated increased CIN2+ diagnoses at the posterior cervix compared to the anterior [ 18].
SDS-PAGE demonstrates increased oligomerization of MAβ(1 42 E22G compared to MAβ(1 42).
Additionally, SVR− patients demonstrated increased pre-treatment chemotaxis to CXCL12 and CXCL10 compared to SVR+ patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com