Sentence examples for demonstrating defects from inspiring English sources

DNA extracted from a subset of pediatric HGGs demonstrating defects in SETD2, IDH1, or H3F3A at G34 and wild-type tumors (n = 36) was analyzed for genome-wide DNA methylation patterns utilizing the HumanMethylation450 BeadChip according to the manufacturer's instructions (Illumina, San Diego, USA) at the McGill University and Genome Quebec Innovation Centre.

In induced cultures, many mitotic cells demonstrated defects in spindle architecture during mitosis.

Taken together, these results demonstrate defects in cell division after UNG2 depletion, consistent with a reduction of CENP-A.

Detailed analysis of the few surviving mice demonstrated defects in B lymphocyte maturation, aberrant meiosis, and accelerated senescence of mouse embryonic fibroblasts.

Our previous studies had demonstrated defects in both LTP and LTD in the D36 mutants and here we demonstrate that, despite similar PKA delocalization in KO and D36 mice, the electrophysiological phenotypes associated with the D36 mutant are not shared by the KO.

GRHL3 -/- mice demonstrated defects in cell migration.

PMNLs from diabetic patients demonstrated defects in LPS-induced apoptosis.

linc Brn1b −/− mice demonstrate defects in proliferation of IPCs.

Furthermore, Dynamin1 knockout mice demonstrate defects in SV endocytosis during strong, but not mild, neuronal activity.

The hippocampus of mutant Tsc2 flox/ko ;hGFAP-Cre mice also demonstrated defects in organization.

Furthermore, studies have consistently demonstrated defects in polymorphonuclear leucocyte (PMN) activity in patients with diabetes, including impaired chemotaxis, phagocytosis and microbicidal functions [ 52].