Sentence examples for demonstrating copy from inspiring English sources

Integration of gene expression with copy number data allows one to determine the genes demonstrating copy number-driven expression as putative oncogenes and tumor suppressor genes.

Whilst SLIT3 demonstrated copy number and expression concordance in 83% (15/18) SCCs but only 53% (10/19) ACs.

The 15 ACs and 15 SCCs found to have concomitant reduced miR-218 and host gene expression also demonstrated copy number loss in SLIT2 and/or SLIT3.

The hybridization profile also demonstrated copy variations among the different isolates.

Potential candidates at chromosomal segment 17q21 that demonstrated copy number gain and overexpression included GEP, TOP2A and HER2.

The TPD52 gene maps to chromosome 8q21.13, and demonstrates copy number increases and overexpression in a variety of cancers [reviewed in 31].

This modification of the CGH method has demonstrated copy number changes as low as 100 kb (Solinas-Toldo et al, 1997).

The amplicon core also includes one additional gene, YPEL2, but for unknown reasons it does not demonstrate copy number dependent overexpression.

Of the 35 probes evaluated, 32 probes demonstrated copy gains in more than 70% of cancer samples whereas 12 probes were able to detect copy gains in at least 70% of CIN2/3 lesions.

When hunting for novel TSGs, chromosomal regions that demonstrate copy number loss in cancer have traditionally been prioritised, whereas regions of copy number gain are highlighted in the search for proto-oncogenes.

Previously we reported an analysis of the CpG methylation analysis data [ 19] but for this reanalysis we concentrated on the methylation status of genes within regions that demonstrated copy number abnormalities.