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The fraction of cells demonstrating bright nuclear fluorescence was maximal (0.58±0.071; mean ± 95% confidence interval) when cells were incubated with the peptide at 15°C, with a significant but smaller fraction of nuclei positive for R9-TAMRA at 4°C (0.33±0.065) and very few cells with nuclear staining at 25°C (0.01±0.016) and 37°C (0.03±0.082).
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Middle row demonstrates bright signal on the ADC map (d) in a polycystic kidney.
NPs that were grown by the route described above demonstrated bright emission under UV excitation.
Lower row demonstrates bright signal on DWI (f; b-value: 800) in a case of xanthogranulomatous pyelonephritis (see also Fig. 10).
Open image in new window Fig. 1 Presentation of diffusion-weighted images (DWI; b-value: 800) and apparent diffusion coefficient (ADC) maps in different entities: Upper row demonstrates bright signal on DWI (a; b-value: 800) and low signal on an ADC map (b) in the case of a clear cell renal cell carcinoma (RCC), with heterogeneous pattern on T2-weighted image (c).
Jupiter demonstrates bright, persistent aurorae around both poles.
The construct was expressed in E. coli and demonstrated bright fluorescence after overnight growth at 37°C and purification.
One founder line demonstrated bright nuclear expression of mCherry in only a small minority of beta cells and was discarded.
Immunofluorescence microscopy demonstrated bright (3 4+; on a scale of 0 4) linear staining of glomeruli, Bowman's capsules and tubular basement membranes for kappa light chain.
4T1 cells stained with aldefluor substrate demonstrated bright green fluorescence, which could not be distinguished from the GFP expression in cells infected with HSV1-GFP.
Images captured at 24 hours post-infection demonstrated bright green fluorescence in virtually all cells, indicating that viable, exfoliated cells from urine can be transduced with adenovirus.
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