Sentence examples for demonstrating a gain from inspiring English sources
In the cohort presented here, the region 3q25 27 represents the minimal region of overlap present in all tumours demonstrating a gain on 3q2.
Recovery from inactivation was significantly more complete in R1242G, demonstrating a gain-of-function component (Fig. 2D).
TP53 is unique among tumor suppressor genes because its alteration not only results in loss-of-function of the product, but also generates a range of mutants demonstrating a gain-of-function phenotype.
These results suggest that the P5L Ank mutant is capable of demonstrating a gain-of-function with respect to extracellular inorganic pyrophosphate elaboration, but this effect is modified by high levels of expression of alkaline phosphatase in ATDC5 cells during hypertrophy and terminal differentiation, resulting in the deposition of basic calcium phosphate crystals.
In conclusion, power to demonstrate a gain in OS limited in these trials; ultimately, if a significant OS improvement is observed in some but not at all trials, this discrepancy might be more attributable to chance than to a truly different drug impact on OS.
We demonstrate a gain in both overall binding energy and overall rank of the known substrates when two screens with a rigid and flexible (up to 15 sidechain dihedral angles) receptor are compared.
Interestingly, our data demonstrate a gain in bw in AMM-exposed fetuses as early as GD20.
Fifthly, by exploiting glutamate as an analogue of the carbamylated K125 (in Cx26K125E), we demonstrated a gain of function Cx26K125E was constitutively open, yet had lost sensitivity to CO2.
A prospective study on previously untreated eyes with perfused ME secondary to BRVO demonstrated a gain of 3 or more BCVA lines in 57% at 1 year [ 14].
In one tumor, a region of 2 Mbp demonstrated a gain in copy number on chromosome 7q, also seen in the corresponding kidney cortex sample.
qRT-PCR analysis also demonstrated a gain in α-tubulin expression and a reduction of the Notch target esr1 (Fig. 2K).
