Sentence examples for demonstrating a defect from inspiring English sources

In contrast, prelamin A/C in LNCaP cells was not only partially localized to the nuclear membrane but also localized inside the nucleus, demonstrating a defect in nuclear envelope formation, similar to that observed in Hutchinson-Gilford Progeria Syndrome.

Again, MG132 caused toxic stress to control and Atg7 −/− cells, but cell death was only markedly elevated in the latter, thereby demonstrating a defect in handling misfolded proteins upon autophagy deficiency.

Stuart Mossman, a visiting clinical fellow, undertook the first passive transfer experiments, using IgG prepared from plasma exchange samples and demonstrating a defect in nerve-evoked muscle responses in the injected mice with little effect on AChR numbers (Supplementary material B79).

Notably, control neutrophils incubated with serum taken from patients with diabetes also demonstrated a defect in phagocytosis, implying that the defect was, in fact, due to defective opsonisation and not to a deficit in neutrophil function per se: in other words, the defect is humoral.

a Four-chamber view demonstrates a defect in the distal portion of the interventricular septum (arrowhead).

Therefore, these lesions have fewer macrophages, including Kupffer cells, than normal liver tissue, and these lesions may demonstrate a defect in the Kupffer phase.

We will not pursue that dispute here except to note that even if the case is made that ID could not count as proper science, which is controversial,[24] that would not in itself demonstrate a defect in design arguments as such.

Interestingly, cells with mutant dyskerin activity also demonstrate a defect in translation of messenger RNAs containing IRES elements [42].

Strain 1F8 demonstrated a defect in melanization, showing much less pigment accumulation than wild type cells (Figure 4B).

The neurons that we analysed in neonate MGC might therefore have been too immature to demonstrate a defect in MHC regulation due to MeCP2 deficiency.

These mice demonstrated a defect in interneuron differentiation and survival, which is associated with functional deficits that may be similar to the subset of ATR-X patients with visual anomalies [9].