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Figure 3 demonstrates that the differentiated cells from spiral ganglion SPCs were able to express glial cell protein GFAP or neural marker βIII-tubulin.
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Taken together, these data demonstrated that the differentiated cells derived from hepatic progenitor cells show great similarity to cholangiocytes in vivo.
Control cells produced type II procollagen, processing it (α1 [II]) and secreting it into the media, demonstrating that the differentiated chondrocyte phenotype was maintained in our culture system.
This finding demonstrates that the HBICA survey effectively differentiated "high-risk" versus "normal" adolescents.
The present study demonstrates that the implantation of adipogenic-differentiated preadipocytes enhances adipose tissue regeneration, as compared with the implantation of undifferentiated preadipocytes, and that cell transplantation-mediated adipogenesis can be further enhanced by the delivery of bFGF.
Our results demonstrate that the highly differentiated 3-D cell culture model can support the natural growth of human noroviruses, whereas previous attempts that used differentiated monolayer cultures failed.
Gene expression analysis demonstrated that the cells differentiated normally in DM.
Quantification of neurite outgrowth from PC12 cells grown in differentiated WJMSCs-conditioned media demonstrates that the neurite length is significantly more than control medium and undifferentiated WJMSCs group.
Immunocytochemistry was performed at 3 weeks after the change from ITSFn to media for differentiation demonstrated that the cells were differentiated into neuronal cells (MAP2+/Tuj1+) (Figure 2F-H), astrocytes (GFAP+) (Figure 2I) and oligodendrocytes (O4+) (Figure 2I).
Though several mechanisms have been implicated in adult beta cell maintenance and renewal [ 2], it has been demonstrated that the proliferation of differentiated beta cells is the major mechanism for the maintenance of adult beta cell mass [ 3].
Elegant, single-cell-based studies from the Drosophila neuroblast system and developing mammalian brain have demonstrated that the generation of differentiated progeny from stem/progenitor cells is tightly controlled.
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