Sentence examples similar to demonstrates reduced efficacy from inspiring English sources

Some patients who developed AAAs demonstrated reduced efficacy.

33 Recent studies of ustekinumab (an interleukin 12/23 inhibitor) have also demonstrated reduced efficacy in PsA patients with prior exposure to TNF inhibitors.

Specifically, ADCs with higher DARs (e.g., DAR 8) were cleared faster and demonstrated reduced efficacy, in spite of higher drug loading, as compared to ADCs with lower DARs (e.g., DAR 2).

Previous work using the F ab′ 2 fragment of A5B7 in the same xenograft model system, comparing single administration of antibody with the administration of the same activity as three separate fractions, demonstrated reduced efficacy as a result of fractionation (Pedley et al, 1993).

Among the reported agents targeting the SYK, the inhibitor fostamatinib (R788) has demonstrated reduced clinical efficacy compared with other therapeutic agents.

We hypothesize that patients receiving the intervention will report better empowerment and self-efficacy and will demonstrate reduced health risk behaviours.

This demonstrates the reducing efficacy of MTX/FA with the increasing prognostic score.

These data suggest that the 5-day intervention demonstrates efficacy in reducing OCD symptoms and may initiate change in parent accommodation that continues to improve after the family returns home.

More importantly, they also demonstrated potent efficacy reducing airway inflammation in a mouse model with low toxicity, indicating a proof of concept that BRD4 inhibitors may offer the therapeutic potential to block the viral-induced airway inflammation.

If the technique demonstrates efficacy, it would reduce the physical and psychological consequences of complications at birth related to persistent OP position.

While some studies demonstrated its efficacy in reducing blood loss but not reducing blood transfusion [ 24, 25].