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The model demonstrates effects on lost disability-adjusted life years and costs over the course of several epidemics of each disease.
Although numerous studies in experimental animals documents toxic effects of PFAS on several organ systems, there are no animal experimental data that directly demonstrates effects on male or female fecundity and possible mechanisms remain speculative [ 7, 8].
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While patients in both studies experienced improvement in quality of life only one of the studies demonstrated effects on IBS symptoms [ 36].
There were also laboratory studies demonstrating effects on animals and cells that seemed to support the observations.
Gene expression analysis demonstrated effects on cell cycle regulation.
Preclinical studies of fetal exposure demonstrate effects on learning, motor behavior, and memory.
The cytokines IL-1, IL-8, IL-10, and TGFβ all demonstrate effects on either tumor growth or metastasis through their interactions with cancer cells.
Primary colony-formation assays in methylcellulose demonstrate effects on tumorigenic potential of these leukemia cells.
Infliximab demonstrated effects on peripheral arthritis and enthesitis.
Studies demonstrating effects on overall arthropod diversity are lacking.
tDCS has demonstrated effects on the excitability of the cerebral cortex.
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