Preoperative airway examination demonstrated bulky soft tissue in the pharynx, grade 2 macroglossia, an enlarged uvula and tonsils, an exuberant gag reflex and a Mallampatti grade II airway.
Ultrasonographic examination of the hip demonstrated a bulky pertrochanteric abscess, with several sinus tracts perforating the fascia towards the surface.
CoMFA and CoMSIA results demonstrated that small bulky and electropositive side chains at R3 position and hydrophobic groups at R7 and R8 positions will increase their activity, and intra-molecular hydrogen bonds between residues 1 and 4 are necessary to maintain the pharmacophoric conformation of RAs.
X-ray crystallographic studies have supported these conclusions by demonstrating that the bulky hydrocarbon adducts of several lesions, including dGAP, adopt multiple conformations relative to the active site of Dpo4 corresponding to the productive, nonproductive, and dead-end complexes inferred from the aforementioned kinetic studies.
A relatively small bulky mass (arrow), that demonstrates slightly and homogeneous enhancement.
Its large size demonstrates that it preferentially accommodates very bulky and hydrophobic residues, such as these found in our studies.
Three dimension quantitative structure-activity relationship (3D-QSAR) studies were performed to highlight the structural requirements of AST analogs, which demonstrated introduction of bulkier substituents on the N-terminus would increase the activity.
Lastly, a system-level antenna comparison study that includes our patch antenna is documented in [45] and demonstrates a performance comparable to an external bulky monopole, whilst yielding far superior performance than a printed alternative.
As she demonstrates, it requires minimal effort to rearrange those bulky buds into a cohesive, blooming display.
A peptide library screening, assisted by accurate measurements of reaction kinetics for selected peptides, demonstrated the preference for bulky and aromatic residues at variable positions Xaa and Zaa [A. Krężel, E. Kopera, A.M. Protas, A. Wysłouch-Cieszyńska, J. Poznański, W. Bal, J. Am. Chem. Soc., 132 (2010) 3355 3366].
