However, as acceptable sampling adequacy was demonstrated, we considered the sample size (n = 92) acceptable for exploring the factor structure in the present study.
One of the main observations of this paper is that the coupling structure and symmetries in this system are not sufficient to guarantee robustness of the heteroclinic behaviour observed in [11], but robustness can be demonstrated if we consider constraints in the system.
Recently, we demonstrated, what we consider a key explanation for the potent synergy between TNF- α and chemotherapy, an up to six-fold increased intratumoural melphalan or doxorubicin concentration in rat sarcomas after ILP when high-dose TNF- α was coadministrated (de Wilt et al, 2000; van der Veen et al, 2000).
To demonstrate this we consider a model with only one exogeneous variable, generalizations being obvious.
To demonstrate this, we consider various identification schemes and compare the bit overhead for the acquisition phase, i.e., the number of bits required to acquire the activated tags.
To demonstrate SS+, we consider its application to two different reliability problems: a linear reliability problem and reliability analysis of an elasto-plastic structure subjected to strong seismic ground motion.
To demonstrate this, we consider again an image represented by sinusoidal function (see above) and use its values determined on N pixels in an image line.
To demonstrate this, we consider six key DNA-damage response (DDR) genes that are frequently altered across four cancers – breast, prostate, ovarian and uterine – and using genomic copy-number and gene-expression data from TCGA [ 41, 42], we identify genes that are altered in a (significantly) mutually exclusive manner with these six DDR genes.
If effectiveness is demonstrated, we are well-positioned to consider inclusion in Clinical Practice Recommendations for DM2 and hypertension.
The same association was also demonstrated when we considered each biological replicate experiment separately and found that the strongest association for each replicate was with rs400547 and linked SNP markers (Supplementary Material, Fig. S2).
