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The validity of our approach is demonstrated using direct comparisons with predictions from the Orr Sommerfeld equations.
Additionally, the prefrontal cortex has been observed to play a role in the top-down regulation of HRV, as demonstrated using direct current stimulation of the dorsolateral area of the prefrontal cortex during viewing of negative images compared to neutral images (images of nature were not used in this study).
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None the less, our previous studies with spirulina protecting from stroke are very similar to those reported above for NT-020 where we demonstrate using direct measures an increase in NPC proliferation in the NT-020 treatment group.
In addition, reduced fatigue has been demonstrated using more direct approaches of separately activating subcompartments of muscles in nerve stimulation.
The relevance of HIF-1α as the main mediator of bcl-2 induced VEGF secretion under hypoxic conditions has been demonstrated using siRNA directed to HIF-1α in M14 cells stably transfected with bcl-2 expression vector ( Figure S1C ).
An important role of Oct4 factor in sustaining pluripotency of preimplantation embryonic cells and mouse embryonic stem cells (ES cells) has been convincingly demonstrated using the directed mutagenesis and RNA interference [ 3- 5].
That uORFs might increase translational efficiency has been hypothesized (Neafsey and Galagan 2007; see also Hood et al. 2009), but no previous examples have been found or directed demonstrated using mutational analyses.
A direct interaction was demonstrated using surface plasmon resonance using a GPVI recombinant protein consisting of N-terminal ligand-binding region (residues 21 234) fused to a C-terminal human IgG domain (figure 5B).
We chose the αMHC promoter because others have demonstrated, using traditional transgenic procedures, that it directs high levels of reporter gene expression specifically in cardiac tissue of early mouse embryos [ 16- 18].
It is demonstrated using four 1D radiative transfer models that are compared in direct mode.
Furthermore, direct interaction between delphinidin and ERα activator site is demonstrated using both binding assay and docking.
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