Mesenchymal stem cells (MSCs) have recently been demonstrated to regulate inflammation in various diseases.
Yet another kinase, homeodomain-interacting protein kinase 2 (hasK2) has been demonstrated to regulate Hippo pathway activity.
Since TET1 has been demonstrated to regulate a series of gene expression, we asked whether TET1 could modulate srGAP3 expression.
In addition, thiol-based redox systems through peroxiredoxins have been demonstrated to regulate several redox-dependent process related diseases.
In line, S100 family members, including S100A6, have been demonstrated to regulate critical processes such as tumor growth, metastasis, angiogenesis and immune evasion [54 57].
Despite their lack of protein coding potential, ncRNAs have been largely demonstrated to regulate the majority of biological processes and have also been largely implicated in cardiovascular disorders.
ARF6 has also been demonstrated to regulate the actin cytoskeleton.
Astrocytes have been demonstrated to regulate BBB integrity in vitro and in vivo [9], [10], [13].
p53, which is regulated by ARF, has also been demonstrated to regulate OB function [9].
PKCη is demonstrated to regulate occludin phosphorylation and TJ permeability in epithelia [18], and blockage of PKCη attenuates occludin hyperphosphorylation.
Recently Gata3 has been demonstrated to regulate trophoblast development in parallel to Cdx2, and both genes are dependent on a third gene, Tead4 [40], [40].
