Exact(46)
Many other functionalities have been demonstrated to function as unnatural internucleoside linkages, including ethers, esters, sulfonates, amines, phosphonates, and amides (Schneider and Benner, 1990a; Li et al., 2002; Bean et al., 2006; Cleaves and Bada, 2012).
We examine the functions that have been determined for several spirochetal OMPs including those that have been demonstrated to function as adhesins, porins or to have roles in complement resistance.
Although initially designed and demonstrated to function as antisense and antigene reagents that inhibit both transcription and translation by steric hindrance, more recent applications have included gene activation by synthetic promoter formation and mutagenesis of chromosomal targets.
Permeable Pavement Structures (PPS), designed to improve drainage of urban paved areas, have been demonstrated to function as hydrocarbon traps with 98.7% efficiency and as powerful in-situ aerobic bioreactors.
The anoctamin gene family comprises 10 members of which two, ANO1 and ANO2 have been demonstrated to function as calcium-gated chloride channels in non-sensory and sensory cells, including photoreceptor and olfactory sensory neurons [17] [19], [21], [22], [34].
Some ALKBH enzymes have been demonstrated to function as nucleic acid demethylases, catalyzing the oxidative demethylation of 1-methyladenine and 3-methylcytosine in DNA and RNA [3], [6], [7].
Similar(14)
Some tDRs have been demonstrated to function independently as biologically active entities.
POLRMT had been thought to function in transcription, but recently this RNA polymerase was demonstrated to function also as a primase (Wanrooij et al. 2008).
The significance of butterfly eyespots has been convincingly demonstrated to serve as an anti-predatory function either by imitation of a predator's own dangerous enemies (intimidation hypothesis) or by deflecting predator strikes toward less-vital parts of the body (deflection hypothesis).
A series of in vitro and in vivo studies clearly demonstrated SR-BI to function as a physiologically and pathophysiologically relevant receptor for HDL metabolism [6].
The corrupting cognitive effect exercised by poems demonstrates their inability to function as Plato knows the beautiful object to function.
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Justyna Jupowicz-Kozak
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