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The developing heart was recently demonstrated to comprise two distinct fields identified through the expression of unique markers, and each giving rise to specific cardiac structures [3], [4].
Additionally, sensory cortex activity has been demonstrated to comprise the signals upon which decisions are made [19] [22], which, when combined with the aforementioned reward association neuroplasticity rules, implies that a significant component of perceptual learning is dependent on sensory cortex changes.
Most of the CD4+CD25+Foxp3+ fraction were neutralized and these results were consistent with that the anti-CD25 mAb selectively depleted those cells expressing the highest levels of CD25, a population recently demonstrated to comprise primarily Foxp3+ cells [38], [39].
By using a PK-sensitivity assay, the rPrPSc molecule in fCJD with 144-bp insertion has been demonstrated to comprise both PrPIns and PrPWt alleles in a case with detectable rPrPSc [ 5].
Recently, the polymicrobial nature of CF has been demonstrated to comprise of a variety of microbial species that include Rothia, Prevotella, Klebsiella and members of the Streptococcus genus [ 5].
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The committee referred to the tendency for interventions to be implemented and evaluated without the collection of baseline data, with sample sizes too small to demonstrate effects, for evaluations to comprise only process evaluation or measure only 'soft' indicators, and for lacking a clear definition of objectives at the outset.
Cloning and sequence analysis demonstrated that this transcript, estimated to comprise less than 5% of the total mesothelin message, utilized an internal splice acceptor site in exon 13 (indicated by the arrowhead in Figure 2B), predicted to encode a protein with an in-frame deletion of 10 amino acids (VATLIDRFVK).
In summary, we have demonstrated that LRs comprise a significant fraction, between6%and10%10%, of all clinically significant mutations in BRCA1 and BRCA2.
One approach to demonstrating health impact comprises a randomized trial in which health outcomes are compared between two patient cohorts, with the imaging biomarker deployed in one cohort.
Recent research has demonstrated that scores comprising biomarkers that show low to moderate correlation between each other and represent different biological pathways could improve discrimination and calibration [ 4, 14, 25].
Global gene expression profiling studies have demonstrated that BC comprises distinct molecular classes with clinical relevance.
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