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Orthologues of clr-1 and clr-2 have been identified in many fungal species but some of the orthologues have been demonstrated to be functionally different.
Little is known about the structural and functional features of plant genes homologous to AtDOG1, except for one type (clade 1) of Triticeae AtDOG1-like genes, which was previously demonstrated to be functionally orthologous to AtDOG1.
TCR-grafted T cells have been demonstrated to be functionally active both in vitro [18] and in vivo [19], [20].
This is the first single biomarker that has been demonstrated to be functionally involved in stem cell maintenance.
Human podocytes (Pods) have been demonstrated to be functionally and structurally injured in the natural history of diabetic nephropathy [ 2].
In bone, multiple P2X and P2Y receptors have been demonstrated to be functionally expressed by both osteoblasts and osteoclasts.
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The derivation of multiple types of edges, notably interior and exterior edge are an improvement over buffer methods which only define forests as either intact or edge, as we conclude that different types of fragmentation are demonstrated to be fundamentally and functionally different.
The target gene selection was augmented by parsing the literature for candidate factors, i.e. yeast and mammalian proteins that have been functionally demonstrated to be involved in trafficking.
As expected, many processes that were enriched have been functionally demonstrated to be controlled by PPARα, including cellular ketone metabolic process, lipid metabolic process, cellular amino acid and derivative metabolic process, peroxisome organization, and mitochondrion organization.
Such modules have been demonstrated to be enriched by functionally-related genes and, generally speaking, are thought to be playing some functional role (despite still uncharacterized in some occasions) [7].
We studied nine rare germline variants within the SIAE gene (chromosome 11), which are among the 12 rare non-synonymous SIAE variants demonstrated by Surolia et al. to be functionally defective in esterase activity or enzyme secretion (11).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com