Sentence examples for demonstrated to be enriched from inspiring English sources

While these genomic locations were ChIP-enriched, cloned and demonstrated to be enriched once more in a validation ChIP experiment, further study will be necessary to demonstrate p53-dependent transcription.

Such modules have been demonstrated to be enriched by functionally-related genes and, generally speaking, are thought to be playing some functional role (despite still uncharacterized in some occasions) [7].

During experimental autoimmune encephalomyelitis (EAE), peripherally expanded Tregs are found to accumulate within the CNS [31], and Foxp3+ Tregs were demonstrated to be enriched in the CSF of MS patients contributing to the hypothesis that natural Tregs may be actively "recruited" to the site of inflammation in MS [23], [32].

In a recent study, genes related to nitrogen metabolism were demonstrated to be enriched among HD stress responsive genes [ 14].

Most of which have now been demonstrated to be enriched at the T. cruzi parasite synapse (Woolsey et al., 2003; Croxford et al., 2005; Barrias et al., 2007).

Globally, a few motifs showed strong correlation with RBf1 and RBf2 peaks, including the E2F and DREF motifs that we previously demonstrated to be enriched at RBf1 binding sites (Acharya et al. 2012).

The CD133+ subpopulation of colon cancer cells was recently demonstrated to be highly enriched in tumour-initiating Co-CSCs, whereas in contrast, CD133− tumour cells did not have tumour-initiating capabilities (O'Brien et al, 2007; Ricci-Vitiani et al, 2007).

In this tumour, a CD133+ subpopulation of colon cancer cells was recently demonstrated to be highly enriched in tumour-initiating colon CSCs (Co-CSCs) that have the ability to self-renew and to recapitulate the bulk tumour population (O'Brien et al, 2007; Ricci-Vitiani et al, 2007).

Basal CD49fHigh cells have been demonstrated previously to be enriched in mammary repopulating units (MRUs) (known as mammary stem cells (MaSCs)) [ 16, 19] and to correspond to the Lin- CD24+ CD29High epithelial cell subpopulation isolated by an alternative method [ 18, 19, 45].

We demonstrated Nef exosomes to be enriched for miRNAs that target key pathways such as cytokine-cytokine receptor interaction and Jak-STAT and MAPK signaling, as well as those that target the viral genome [ 4].

In particular, we were interested in following up on a prior paradoxical observation that demonstrated DNA methylation to be enriched at DNase hypersensitive, early-replicating euchromatin in non-cancer cell lines [ 14], suggesting that the effects of a DNA demethylating agent would be more likely to target this gene- and transcription-rich genomic compartment.