Sentence examples for demonstrated to be active from inspiring English sources

A previous study investigated the activities of compounds demonstrated to be active in zebrafish embryo bioassays, in both zebrafish and mammalian cell lines [56].

In fact, not only PMX, as above reported, has demonstrated to be active as single agent but CPT-11 also has demonstrated activity, although modest, in pancreatic cancer (Wagener et al, 1995; Klapdor and Fenner, 2000; Pizzolato and Saltz, 2003).

In clinical trials, this anti-HER2 monoclonal antibody has been demonstrated to be active as a single agent and has been shown to improve survival when it is added to two standard chemotherapy regimens in patients with metastatic breast cancer.

A novel oral prodrug, AV-101 (l-4 chlorokynurenine), which, in the brain, is converted into one of the most potent and selective GlyB site antagonists of the NMDAR, has been demonstrated to be active in animal models of neuropathic pain.

Its essential oil (perilla oil) has been previously demonstrated to be active against S. aureus.

Interestingly, while ATG12 has not been found in kinetoplastids, autophagy has been demonstrated to be active in Leishmania spp. and play a key role in parasite virulence [59].

Most of the compounds demonstrate to be active against α-glucosidase, and quite inactive/completely inactive against β-glucosidase.

The released PTH was demonstrated to be biologically active using an in vitro assay.

Pyrrhotite has demonstrated to be electrochemically active and beneficial for the capacity retention in lithium test cells.

MGBs with an alkene link between the two N-terminal building blocks were demonstrated to be most active with IC50 values in the range 30 500 nM and therapeutic ratios in the range 10 >500.

Among the synthesized catalysts, the fibrous shape demonstrated to be most active towards soot oxidation: it reduced the peak combustion temperature from 600 °C (non-catalytic combustion) to 375 °C in tight contact, 428 °C in prolonged loose contact (see detailed definition in the text), and 553 °C in loose contact.