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The upregulation of myocellular DGAT1 has been demonstrated to augment TAG storage, decrease cellular DAG, and protect against high fat diet induced IR (Liu et al. 2007).
For example, a combination of NF-κB inhibitor, such as parthenolide or curcumin, with PXL has been demonstrated to augment the therapeutic efficacy in various cancer models [5].
A brief exposure of skin to a low-power, non-tissue damaging laser light has been demonstrated to augment immune responses to intradermal vaccination.
Additionally, plasmid gene transfer of SDF-1 has been demonstrated to augment neovascularization through VEGF [ 50].
Inducible expression of rat MUC4 in human A375 melanoma cells has been demonstrated to augment primary tumor growth [ 25] and metastasis [ 26] in a nude mouse xenograft model.
An overexpression of c-Src in murine mesangial cells has been demonstrated to augment NF- κB activation and nitric oxide production [ 22].
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Various conventional chemotherapeutic agents have been demonstrated to synergistically augment TRAIL-induced apoptosis through induction of DR5 expression.
In the KCI-18 RCC model, treatment of kidney tumor-bearing mice with genistein alone demonstrated a tendency to augment the growth of kidney tumors compared to control mice whereas radiation slowed the growth of kidney tumors.
We demonstrate a method to augment the resolution of N-body merger trees by grafting in branches of Monte Carlo merger trees with higher resolution, but which are consistent with the pre-existing branches in the N-body tree.
It was also demonstrated that inflammation might act to augment disease progression via its ability to stimulate neuronal Aβ production in the progression of AD, and to facilitate amyloid deposition.
Of note, several studies demonstrated that MSCs possessed great capacity to augment autophagy.
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