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The model successfully captured measured data for all investigated media and demonstrated the implications of the poorly-understood shift in gas percolation threshold with improved gas percolation in reduced gravity.
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Recent reports convincingly demonstrated the implication of p63 in epithelial stem cell renewal potential, as the absence of p63 was shown to induce a loss of proliferative potential of epidermal [5], [6], corneal [7] or thymic epithelial cells [6], [8].
Advances in the knowledge of renal neoplasms have demonstrated the implication of several proteases in their genesis, growth and dissemination.
Our previous studies demonstrated the implication of Rac1 in mediating NPM ALK-dependent iNPM ALK-dependentells.
It was also demonstrated the implication of many allelic variations in CYP1B1 in modulating the incidence of several types of cancers [ 98, 99].
Consistent evidence has demonstrated the implication of fructose or HFCS in the development of NAFLD in several animal models [ 17, 33– 33].
Ample studies have demonstrated the implication of histone hyperacetylation in gene transcription but also in silencing gene expression of others [ 27, 44, 45].
Furthermore, our experiments using a neutralizing antibody or recombinant protein demonstrated the implication of autocrine IL-6 signalling in STAT3 activation in human gastric cancer cells.
Moreover, concomitantly with our work, it has been demonstrated the implication of human transporters in tumor progression in a transport-independent manner.
Finally, in terms of biological functions, a lot of studies demonstrated the implication of class I proteins in chemotaxis in Dyctiostelium [ 39– 41].
Although these studies definitely demonstrated the implication of the iron III)–hydroperoxo species, it was not clear whether the catalytic activity was from the iron III)–hydroperoxo or not.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com