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Recent reports convincingly demonstrated the implication of p63 in epithelial stem cell renewal potential, as the absence of p63 was shown to induce a loss of proliferative potential of epidermal [5], [6], corneal [7] or thymic epithelial cells [6], [8].
Advances in the knowledge of renal neoplasms have demonstrated the implication of several proteases in their genesis, growth and dissemination.
Our previous studies demonstrated the implication of Rac1 in mediating NPM ALK-dependent iNPM ALK-dependentells.
Ample studies have demonstrated the implication of histone hyperacetylation in gene transcription but also in silencing gene expression of others [ 27, 44, 45].
Furthermore, our experiments using a neutralizing antibody or recombinant protein demonstrated the implication of autocrine IL-6 signalling in STAT3 activation in human gastric cancer cells.
Moreover, concomitantly with our work, it has been demonstrated the implication of human transporters in tumor progression in a transport-independent manner.
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The model successfully captured measured data for all investigated media and demonstrated the implications of the poorly-understood shift in gas percolation threshold with improved gas percolation in reduced gravity.
The simulation results demonstrate the implication of varying the number of the lanes, the number of TV channels provided and access network technologies in Figures 14, 15 and 16.
To the contrary, inhibition of IL-1R signals from downstream can curtail miR-146a/b level, demonstrating the implication of microRNAs in a negative NF-κB feedback loop of secretory regulation between IL-1α and miR-146a/b (Freund et al., 2010).
To further demonstrate the implication of GIRK channels in SDC, clonidine effects were studied while applying voltage ramps from −150 to +10 mV.
The results also demonstrate the implication of the brainstem in mediating these responses in humans and speak for a broad involvement of light in the regulation of brain function.
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