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On the plus side, RedEnvelope demonstrated that once it drove people to its site, they bought something.
Bert's work on conjoined rats demonstrated that, once their wounds had healed, the animals developed a single, shared circulatory system.
"He demonstrated that once you had this formula you could make all these tiny variations in your work, which keeps it very interesting," he added.
Long-term studies have consistently demonstrated that once the patient's own voluntary efforts to cut down on drinking have repeatedly failed, sustained abstinence is the practical answer.
Over eight seasons (and a television movie), "24" demonstrated that once the real villains are unmasked, the story goes flat; the conspiracy is always from within, and it's hard not to make master plotters look cartoonish.
For example, in studies beginning in the 1970's, Dr. Baruch Fischhoff, a professor of social and decision science at Carnegie Mellon University, and other psychologists have demonstrated that once people know the outcome of an event, they routinely overestimate how much predictive information they had beforehand.
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Mr. Putin has rarely wanted for a dramatic gesture, and the dismissals demonstrated that point once more.
Numerous studies have demonstrated that once-daily regimens are as safe or safer than multiple-dose regimens with equal efficacy.
Second, and as aforementioned, trials with systematic dose titration demonstrated that once-daily basal insulin achieves the currently recommended glycemic levels in many patients with type 2 diabetes (27, 29).
The PREVAIL phase III clinical study demonstrated that once-daily USL255 (200 mg/day) significantly improved seizure control and was safe and generally well tolerated with few neurocognitive side effects.
Results from the GLOW2 study demonstrated that once-daily NVA237 50 μg is an efficacious and safe LAMA in patients with COPD over 52 weeks of treatment, and is comparable to tiotropium, the current gold standard for the treatment of COPD.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com